IBS, Genetics and Supplementation

There is no known cure for IBS. If you have IBS, doctors can help you manage symptoms and prevent flare-ups so that you can live a normal life.

The main IBS management strategies include:

Eating foods high in dietary fiber Drinking lots of water Regular exercise A healthy & regular sleep schedule Avoiding stress Avoiding triggering foods

How peppermint oil helps with IBS: Peppermint oil may improve stomach pain and bloating by relaxing gut muscles [R, R, R]. Typical doses are 180-200 mg, 3-4 times a day [R, R, R, R, R, R]. Some special pills release the oil slowly in your gut, making it more effective. Doctors call this enteric-coated peppermint oil [R].

The best supplement that I personally have found for my IBS and my daughters is Fulvic acid, this is the one I use: https://www.blackoxygenorganics.com/sbachman

The genetics that play a role in IBS: In people with TNF gene variant, adding a probiotic may improve IBS symptoms The DAGLB gene variant correlates with IBS. It likely reduces the levels of cannabinoids, which are important for gut health and pain control. Exercise can help boost cannabinoids People with IBS carrying the CRHBP gene variant may be more sensitive to stress. For this reason, you should take special care to reduce stress.

Stress reduction may be more effective at improving IBS in people with certain COMT gene variants

Genes involved in IBS may play a role in : Bile production and release (KLB) Gut movement (HTR3E) Pain perception (HTR3E) Immune system activity (TLR9)

The American College of Gastroenterology recommends peppermint oil for IBS symptom improvement.

Conclusions Enteric-coated peppermint oil is a safe and effective therapy for the relief of abdominal pain and global symptoms and in adults with IBS.

If you would like to have a genetic report ran I would recommend using the company I used, https://get.selfdecode.com/guthealth/?a_aid=5f7baa4fb7c3f...

Fulvic acid additional uses: • Increased energy • Alleviates anemia • Chelates body toxins • Reduces high blood pressure • Magnifies the effect of herbal teas and tinctures • Chelates all monovalent and divalent metals • Is a powerful natural electrolyte • Restores electrochemical balance • Stimulates body enzyme systems • Helps rebuild the immune system Reported claims of external beneficial use: • Treating open wounds • Healing burns with minimum pain or scarring • Eliminating discoloration due to skin bruises • Killing pathogens responsible for athletes’ foot • Acting as a wide spectrum anti-microbial and fungicide • Treating rashes and skin irritations • Helping to heal cuts and abrasions • Helping heal insect bites and spider bites

The Fulvic Miracle List – Jackson, William R. (1993). Humic, Fulvic and Microbial Balance: Organic Soil Conditioning. Evergreen, Colorado: Jackson Research Center.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337770/